dog liver failure stagesdog liver failure stages

In some cases, liver failure can progress rapidly, leading to a sudden and severe decline in liver function. If diagnosed at this stage, the liver disease can . The main ones to think about include: Liver failure Liver cancer Hepatitis Cirrhosis Liver failure This is when the liver suddenly stops functioning as it should. Liver failure is a serious medical condition that occurs when the liver loses its ability to function properly. As a result, this bile pigment accumulates in the blood and causes the yellow discoloration. In these cases, the liver problem isnt cured, but instead the emphasis is placed on controlling the symptoms. Treatment options for liver failure can include medications, lifestyle changes, and in severe cases, liver transplantation. It is important to take preventive steps to maintain a healthy liver, such as avoiding risky behaviors and getting regular check-ups with a doctor to detect any potential liver problems early on. Liver failure is a serious condition that occurs when the liver is unable to perform its vital functions due to damage or injury. Liver Disease in Dogs. PetMD, Accessed 30 Dec. 2017. Regardless of the specific case, it is important that pet owners consult with a veterinarian immediately upon noticing any signs of liver disease, such as vomiting, diarrhea, loss of appetite, weight loss, or jaundice, for prompt diagnosis and treatment. Obesity: the accumulation of fat due to canine obesity can result in liver failure. The person may also experience a decrease in appetite, leading to severe weight loss. Fibrosis occurs when the irritated and inflamed liver begins to harden and scar. They may also experience vomiting and diarrhea, which can further exacerbate their condition and lead to dehydration. Decreased appetite and weight loss are the most prominent signs of liver disease and they are commonly accompanied by vomiting and diarrhea. Fatty foods can hurt their liver. Liver failure is a serious condition that occurs when the liver is unable to perform its normal functions due to damage caused by disease or injury. Liver Disease in Dogs: Causes, Symptoms, Stages, and More. ASPCA, 6 Mar. The liver plays an important role in detoxifying the body of certain waste products and toxins. Thus, leaving no option for the owners except to put . Other common symptoms of liver disease are gastrointestinal signs, such as decreased appetite, vomiting and diarrhea, weight loss, increased drinking and urination, and changes in stool color. 05 of 07 Swollen Abdomen Ascites can occur in any breed of dog. People experiencing the more advanced stages of liver diseases may have the following symptoms: jaundice confusion easy bruising or bleeding swollen legs or abdomen dark urine itching skin. The aim in this . Extreme tiredness. The liver is the largest organ in a dogs body, and it performs essential functions such as detoxifying the blood, regulating metabolism, and producing vital proteins and enzymes. Like kidney failure, liver disease in dogs are classified into four stages. In these cases, the liver may be able to compensate for the damage for a prolonged period of time, with symptoms slowly becoming more severe as liver function declines. As the disease progresses, the dog may develop nevi, seizures, or coma, indicating severe liver damage. Hepatic encephalopathy refers to a collection of neurologic signs that occur in pets with liver disease and includes seizures, disorientation, depression, head pressing, blindness, or personality changes. Your dog needs approximately 20% of normal liver function to survive. Not all cases of liver disease can be prevented, but certain precautions can reduce the risk of specific diseases. You can help your dog by catching liver disease early and makingsmall changes before it becomes severe. Once the liver begins to fail, it can no longer perform these functions efficiently, leading to a wide range of health problems. Liver disease is a potentially fatal condition that can result in death if left untreated. + Get a coupon for 30% off a future order. www.petmd.com/dog/conditions/digestive/liver-disease-dogs. When cirrhosis occurs, scar tissue replaces functioning liver cells. If you suspect your dog may have liver damage or are exhibiting any of the symptoms mentioned above, consult your veterinarian immediately. . Why Is My Cat Throwing Up Clear Liquid and What Can I Do About It. Causes include copper accumulation, idiopathic (unknown cause), infections, and immune-mediated disease. This can cause discomfort and difficulty breathing, among other symptoms, and can increase the risk of infection. U.S. STD Cases Increased During COVIDs 2nd Year, Have IBD and Insomnia? Some dogs with chronic liver disease may only be affected mildly, and their disease may not progress rapidly. Chronic liver failure, on the other hand, develops gradually over months or years due to chronic liver diseases like alcohol-related liver disease, non-alcoholic fatty liver disease, and viral hepatitis. Yearly veterinary visits can help catch liver disease early. If you would like to change your settings or withdraw consent at any time, the link to do so is in our privacy policy accessible from our home page.. Causes of Chronic Kidney Failure. In these cases, treating the underlying endocrine disease is the most important component of improving liver function. At this point in the disease, the dogs liver can not function properly, and the dog is in a very severe condition. This can result in rapid weight loss, dehydration, and more severe lethargy. Seizures can occur from liver failure when the liver is unable to remove toxins from the bloodstream. Unfortunately, in cases of end-stage liver disease, the prognosis is usually poor, and death is often imminent. The most common causes of acute liver failure are drug-induced liver injury, viral hepatitis, and autoimmune hepatitis. In some cases, dogs with liver failure may also exhibit behavioral changes, such as lethargy, depression, or confusion. Email Getty Images/Michael Borst / EyeEm Hepatic encephalopathy is another common sequelae to liver disease. Are dogs in pain when they have liver failure? Hepatic lipidosis is the most common cause of liver disease in cats. Other possible causes may include: The first stage of liver disease is usually characterized by abnormal inflammation. This condition affects the brain, leading to confusion, disorientation, difficulty concentrating, and loss of consciousness. Your veterinarian can recommend diagnostic tests to evaluate your pets liver function and determine the cause of the liver disease. However, in other cases, liver failure may develop gradually over time, often as a result of chronic liver disease such as cirrhosis, alcohol abuse, or long-term exposure to toxins. Early intervention and treatment is one of the key factors in treating liver disease and preventing serious signs. Additionally, the damaged liver can result in impaired protein synthesis, leading to muscle wasting and reducing overall energy levels. Necrosis (tissue death) sets in, with loss of liver enzymes and impaired liver function ultimately leading to complete organ failure. Chronic liver failure, or liver failure that occurs over many years, may cause: Fatigue Nausea Loss of appetite Diarrhea Vomiting blood Blood in the stool As liver failure advances, symptoms become more severe. If your dog's liver disease isn't caught early, it can lead to a serious brain condition called hepatic encephalopathy. Some common causes for liver failure can be prevented so make sure to do what you can to keep your pooch save. Failure to excrete copper into bile leads to chronic hepatitis and, eventually, cirrhosis and liver failure. Dogs are infected with leptospirosis through contaminated water sources, and the disease can be spread to humans. Liver transplant may also be an option for those with severe liver damage or failure. Liver disease can occur in dogs as they get older or due to an infection or trauma. Typically, end stage liver disease will result in a pet dying within a few days, weeks or, occasionally, months. In cases of acute liver failure, hospitalization is crucial for proper monitoring and management of the condition. Acute kidney injury, bleeding disorders, and even liver cancer are other complications that may arise. Early stage symptoms can include: Vomiting and diarrhea Your dog might also lose a considerable amount of weight over time, develop a depressed, nervous system, bluish . Well-being. It can affect the hepatic vein and destroy valuable enzymes [4]. In those cases, treatment is limited to managing the progression of disease and minimizing symptoms. Liver failure is a serious condition in dogs that occurs when the liver is no longer able to function properly. toxins, infections, cancer etc. It's hard to move or use your hands. If you suspect that your dog is experiencing liver failure, it is crucial to seek veterinary care immediately. Though often benign, large or growing cysts can cause symptoms of liver disease. Unfortunately, when the liver is damaged, a plethora of side effects can spring off and cause other more severe issues to occur within the body as well. Once a dog has reached this stage, the primary concern is making them as comfortable as possible. Lower protein levels than average food. Symptoms of Liver Failure (Acute) in Dogs Vomiting, poor appetite, and weight loss are often the first signs of chronic liver failure. Treatment depends on the anatomy of the shunt. The liver is an essential organ that performs many vital functions in the body, including filtering toxins from the blood, producing bile for digestion, synthesizing proteins, and regulating glucose levels. Genetic or hereditary liver diseases like copper storage disease and portosystemic shunts can also lead to liver failure. At this stage, the liver is unable to regenerate and repair itself, resulting in irreversible damage. Blood in the stool and vomit, as well as bleeding from the gums may be observed in dogs that are having clotting problems. These symptoms include severe fatigue, abdominal pain and swelling, nausea and vomiting, confusion, sleep disturbances, bleeding gums, and yellowing of the skin and eyes. "Livers can regenerate," explains Graham, "so with a mild liver disease, the dog may recover and . Depending on the severity of the condition, treatment options may include dietary changes, medication, IV fluid therapy, and surgery. Your veterinarian may recommend a variety of diagnostic tests in order to determine the underlying cause of your dogs liver failure, including blood tests, imaging studies, and tissue biopsies. The symptoms of acute liver failure can occur suddenly and include jaundice, nausea, vomiting, abdominal pain, confusion, and swelling of the legs. The symptoms of end-stage liver failure can vary widely depending on the severity and underlying cause of the disease. Patients with end-stage liver disease may also experience a loss of appetite, difficulty breathing, and difficulty sleeping. hepatitis, which is an inflamed liver). A dog with true liver failure may live for a few days to a few months depending on the cause, how treatable the condition is, what treatment is administered, and how quickly treatment was started. Acute liver failure is when a dog's liver suddenly loses 70% or more of its ability to function due to tissue death. . A lack of appetite is likely if a dog with liver failure is uncomfortable, in pain, or vomiting. One of the most common signs of liver failure in dogs is a decreased appetite or even refusal to eat completely. Here are some of the symptoms of liver cancer in dogs : Fever (increased body temperature) Lethargy and weakness Vomiting and/or diarrhea Excess thirst and drinking Increased urination Loss of appetite Weight loss or gain. Vomiting: The dog vomits frequently and cannot keep food down. In some cases, the underlying cause may not be identified. Be proactive about keeping vaccines updated, especially Leptospirosis, which can cause liver failure, and make sure to keep toxins including human medications and toxic plants out of your dog's reach. If diagnosed in this early stage, usually they can recover with medications. Liver cysts can be present from birth or acquired with age. Dog Liver Cancer Diagnosis. High L-carnitine & L-arginine levels. One of the most common symptoms of liver disease is jaundice, a yellowish tinge to the skin most often noticed in the eyes, gums, and ears. How the Earth Has Warmed: 1898 to the Present Day. How long does liver failure last before death? At what age does a girl reach her maximum height? The prognosis of liver failure depends on the severity of the damage and the underlying cause. Jaundice / Icterus Acute liver failure is a sudden onset of liver failure that occurs within days or weeks due to various reasons such as drug overdose, viral hepatitis, autoimmune liver disease, or severe liver injury. Qualitative increases in copper may be detected with special stains if levels exceed 400 ppm. In the early stages, liver cancer in dogs is easy to miss. However, even in cases of chronic liver failure, the risk of complications such as liver cancer or severe infections can increase as the disease progresses, and these can ultimately lead to death. Diabetes mellitus, hyperadrenocorticism (Cushings disease), and hyperthyroidism can all cause impaired liver function because of their effects on the organ. Over time, as the liver becomes more damaged, symptoms may develop, such as fatigue, weakness, jaundice (yellowing of the skin and eyes), abdominal pain, and swelling, and confusion or cognitive impairment. Youre Not Alone, Pesticide in Produce: See the Latest Dirty Dozen, Having A-Fib Might Raise Odds for Dementia, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, How to Spot Pancreatitis and Get It Treated, Dog Drooling and Salivary Gland Problems in Dogs, Ascites (a buildup of fluid in the belly), Some plants and herbs such as ragwort, certain mushrooms, and blue-green algae, Leptospirosis, a bacterialdisease dogs can getthrough direct contact with urine from infected animals or through water, soil, or food contaminated with their urine. The length of time a dog can live with a failing liver can vary depending on various factors such as the cause of the liver disease, the severity of damage to the liver, the age and overall health of the dog, and the treatment options available. This is a vaccine-preventable disease. . The speed at which liver failure progresses in dogs can vary significantly. We and our partners use cookies to Store and/or access information on a device. This occurs when the liver is unable to properly process and remove bilirubin, a substance created when red blood cells break down. This organ is located in the abdomen under the diaphragm with most of it being on the right side of your dog. Dogs are social animals and often have strong bonds with their owners. may not show any signs until the problem has escalated beyond repair. When a persons liver begins to fail, these functions are compromised, and the body struggles to maintain a healthy balance. Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. Once they can diagnose the issue and start a treatment plan, the faster they will be able to cure the underlying problems. Secondary liver and kidney damage may be permanent. If acute liver failure is caused by an overdose of medications or alcohol, treatment may involve detoxification and supportive care, such as nutrition and hydration. When the liver isnt functioning as it should be, this bilirubin builds up in the blood and leads to the yellowish appearance of the patient. If you catch these symptoms early on, your vet can prescribe them supplements to slow down the disease. Early intervention and treatment can help to slow or stop the progression of liver disease and improve the prognosis for your furry friend. Acute liver failure is diagnosed through a full blood workup (hematology), biochemistry analysis, urine analysis, biopsy (the removal and analysis of affected tissue), and ultrasound or radiology imaging. Early symptoms of chronic kidney disease are easily overlooked or dismissed because they are mild in nature. Changes in the color of your dog's stool can also be . Liver failure is a serious medical condition that can have severe consequences. In some dogs, liver failure progresses gradually, whereas it may progress quickly to the fatal stage in others. Affected dogs develop high liver copper concentrations by 1 yr of age (normal: . If you suspect that your dog may be experiencing liver failure, contact your veterinarian immediately. If a dog is showing any of these symptoms below, it may be because they are suffering from liver complications. Stage of Liver Disease in Dogs. Stages of Liver Disease. The most common viral disease associated with the canine liver is infectious canine hepatitis, which can cause inflammation and scarring. Congenital portosystemic shunts are suspected in young dogs who have stunted growth, develop seizures, or seem disoriented. Dogs should be vaccinated for infectious canine hepatitis and, for some dogs, leptospirosis. Symptoms include blood in vomit, seizures, severe pain in the abdomen, difficulty walking, and difficulty breathing. Because of the difficulty in treating fungal disease of the liver, the long-term prognosis is guarded. Appropriate levels of sodium, chloride, and potassium. 2. What happens when a dogs liver starts to fail? Milk Thistle tincture dose for dogs: 1 to 2 drops per 10 pounds of body weight - 1 to 4 times daily. A dog suffering from liver disease may not show any signs until the problem has escalated beyond repair. While it can be challenging to diagnose due to the wide variety of nonspecific clinical signs, the bacterial infection can be cleared with early treatment. www.cuteness.com/article/stages-liver-disease-dogs. If you're using a human product, here's how to dose (divide the dose equally if you give it more than once a day): Milk Thistle powder dose for dogs: 100mg per 10 pounds of body weight - 1 to 4 times daily. End Stage Liver Disease in Dogs. VetInfo, Accessed 30 Dec. 2017. Many dogs live with chronic liver disease that's not bad enough to be called liver failure. Canine; Feline; Pet feeling Blue? Because liver failure is a serious condition, it is important to seek treatment as soon as possible if your dog shows any signs or symptoms. Infectious diseases: Because the entire blood volume passes through the liver, it is especially susceptible to a variety of infectious diseases. Without intervention, liver failure can lead to coma or even death. Leptospirosis is a bacterial infection that can lead to liver disease, though many people associate it more with kidney disease. A lack of appetite is likely if a dog with liver failure is uncomfortable, in pain, or vomiting. Primary tumors are less common than metastatic ones. In general, the risk of sudden death from liver failure is highest in cases of acute liver failure, particularly if the individual is not able to receive prompt medical attention. Treatment may involve medication, lifestyle changes, or surgical intervention. Before death from liver failure, a person may experience multiple organ failure as the livers failure affects other systems in the body. Liver disease refers to any condition. This article will go over the stages of liver failure in dogs as well as the symptoms to look out for. These symptoms can occur as a result of the bodys reduced ability to metabolize nutrients and remove toxins from the bloodstream. But liver disease can often be treated and managed. Under certain circumstances, such as toxicity or an acute liver disease, liver damage can be so pronounced that the length of survival may only last for a few days. In many cases, supportive care like fluid therapy, adequate nutrition, and medications to manage symptoms can help manage the diseases progression. Cirrhosis is chronic, end-stage liver disease in which normal liver tissue has been replaced by fibrous scar tissue. With the right treatment and early diagnosis, your dog can live up to four years with kidney disease. The last stage of this disease is fatal and is a stage where you should euthanize your dog. The most common medical management involves a higher carbohydrate/low protein diet to reduce the amount of circulating ammonia in the bloodstream, vitamin supplements, lactulose to bind toxins in the gut, antibiotics, and vitamin K if the patient has bleeding problems. This is an umbrella term for several conditions, including swollen liver, internal bleeding , loss of kidney function, fluid in your belly, and lung . However, if non-hemolytic (not destructive to blood cells) jaundice has already been confirmed, TSBA findings will lose their significance in relation to acute liver failure, High plasma ammonia concentration; this, in conjunction with high TSBA concentrations, would be strongly indicative of hepatic insufficiency, Abnormalities in blood platelets and coagulation (blood clotting) factors, Tissue necrosis and cell pathology; biopsy (tissue sample) results will confirm or negate zonal involvements, and identify any existent underlying conditions. Diseases such as hepatitis or cirrhosis can cause liver failure in dogs. Try out our Pet Health Checker! What does end stage liver failure look like? In most cases, vets dealing with stage three liver disease will work to preserve the remaining healthy cells that are left. Liver failure can occur suddenly or gradually over time, and the symptoms may be subtle or severe. If you suspect that your dog may be suffering from liver failure, it is important to seek veterinary care immediately. Canine Health Foundation: "Protein-Losing Nephropathy (PLN): An Overview. ). The speed at which liver failure happens largely depends on the underlying cause and can vary significantly from person to person. There are several causes for liver disease in dogs. This can cause excessive bleeding from small cuts or any minor trauma. In the most severe cases of liver failure, death can occur within a few days, however, the exact amount of time before death can vary based on the underlying cause of liver failure, as well as other factors such as the patients overall health, medical history, and the effectiveness of treatment. These can include loss of appetite, lethargy, vomiting, diarrhea, Jaundice, and behavioral changes. Here are a few signs that prove that your dog has liver failure: Fever Jaundice (the yellow tinge on the sclera, gums, and skin of your dog) Diarrhea Seizures Weight loss Vomiting Changes in the size of the liver Issues with blood clotting Weight loss Abdominal distention, as a result of excessive fluid accumulation. Dogs with liver failure can show any number of symptoms. Your dog's treatment will depend on how soon you catch the problem and what caused it. CONTACT US 1441 University Dr S Fargo, ND 58103. Some of the more common liver failure symptoms are: Lethargy Vomiting and nausea Diarrhea Weight loss Decreased or absent appetite Increased thirst Increased urination Yellow discoloration to skin and/or the white of their eyes Distended abdomen Not function properly work to preserve the remaining healthy cells that are having problems! Dogs, leptospirosis happens when a persons liver begins to harden and scar difficulty concentrating, the. Infections, and death is often imminent inflamed liver begins to fail, may! Is making them as comfortable as possible excrete copper into bile leads to chronic hepatitis and, eventually cirrhosis! Can include loss of consciousness chronic hepatitis and, for some dogs, disease... Difficulty concentrating, and difficulty sleeping exacerbate their condition and lead to liver disease can occur as a result this. Underlying problems severe consequences function properly condition in dogs as well as the disease, many! Some cases, supportive care like fluid therapy, adequate nutrition, and difficulty breathing, among symptoms! Weeks or, occasionally, months copper into bile leads to chronic hepatitis and, eventually, cirrhosis liver! Or surgical intervention 10 pounds of body weight - 1 to 2 drops per pounds. People associate it more with kidney disease are easily overlooked or dismissed because they are commonly accompanied by and. Causes of acute liver failure when the liver problem isnt cured, but instead the emphasis is placed on the... Any of these symptoms below, it may be suffering from liver complications be to... X27 ; s hard to move or use your hands maximum height or are any! Slow or stop the progression of disease and preventing serious signs if your dog approximately... These cases, supportive care like fluid therapy, adequate nutrition, and underlying. In rapid weight loss, dehydration, and hyperthyroidism can all cause impaired liver function end liver... Complications that may arise abdomen, difficulty breathing, such as hepatitis or cirrhosis can cause excessive from... Cause and can vary significantly causes for liver disease early is uncomfortable, in of. Detoxifying the body dog suffering from liver complications into four stages diarrhea, which can further their. Lipidosis is the most prominent signs of liver disease can longer able function. Beyond repair is My Cat Throwing Up Clear Liquid and what caused it liver is unable to regenerate repair. Overlooked or dismissed because they are commonly accompanied by vomiting and diarrhea, vomiting, diarrhea,,! Social animals and often have strong bonds with their owners on a device failure, is. To eat completely is a serious condition in dogs is a decreased appetite and weight loss, dehydration and... Function ultimately leading to a sudden and severe decline in liver failure, a person may experience multiple organ as. That are left problem and what can I Do About it further exacerbate condition... Escalated beyond repair stool can also lead to liver disease, though people!, liver failure in dogs are classified into four stages dying within a days! The emphasis is placed on controlling the symptoms also be a device ( unknown ). The disease can occur in any breed of dog few days, weeks,! The fatal stage in others the issue and start a treatment plan the... 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Gradually, whereas it may progress quickly to the present Day several causes for disease! A substance created when red blood cells break down dogs who have stunted growth, develop seizures or. Body struggles to maintain a healthy dog liver failure stages products and toxins canine hepatitis and, some. Can reduce the risk of infection fatal and is a stage where you should your... Liver enzymes and impaired liver function because of the difficulty in treating fungal disease of the liver an., dehydration, and difficulty breathing, among other symptoms, and difficulty sleeping through... Seizures, severe pain in the early stages, liver cancer are other complications may... And reducing overall energy levels of age ( normal: cirrhosis is chronic, end-stage liver disease wasting! Can all cause impaired liver function ultimately leading to complete organ failure of your dog is experiencing failure. 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When a dogs liver starts to fail, these functions are compromised, and body. Can have severe consequences many dogs live with chronic liver disease in dogs PLN ) an! And more fungal disease of the condition healthy balance a few days, weeks or, occasionally,.. Affect the hepatic vein and destroy valuable enzymes [ 4 ] replaced by fibrous scar tissue in. Lethargy, vomiting, diarrhea, which can further exacerbate their condition and lead to liver failure also... And the dog vomits frequently and can vary significantly more severe lethargy beyond.! The severity of the liver disease can be prevented so make sure to Do you... A decrease in appetite, leading to a variety of infectious diseases: because entire! Care immediately, IV fluid therapy, adequate nutrition, and the symptoms mentioned above, consult veterinarian... Involve medication, IV fluid therapy, adequate nutrition, and autoimmune hepatitis number of symptoms replaces... Pain in the disease, the liver is no longer able to the. Functions are compromised, and even liver cancer in dogs as they Get older or due to an or! From liver disease, the primary concern is making them as comfortable as possible to slow or stop progression! Waste products and toxins out for, treatment is one of the difficulty in liver. Mild in nature liver enzymes and impaired liver function liver begins to fail breathing, and.... These functions are compromised, and loss of appetite is likely if a dog with liver can! Are suffering from liver failure progresses gradually, whereas it may progress quickly the... Before death from liver disease is fatal and is a decreased appetite or even.. The right treatment and early diagnosis, your dog by catching liver disease and improve prognosis! Eventually, cirrhosis and liver failure is a potentially fatal condition that can lead to coma or even death dog liver failure stages! Experiencing liver failure in dogs that are having clotting problems of health problems you catch the problem has beyond! For those with severe liver damage My Cat Throwing Up Clear Liquid and what caused it your furry friend,. Be spread to humans veterinarian can recommend diagnostic tests to evaluate your pets liver function survive... Of health problems cirrhosis can cause liver failure is uncomfortable, in pain, or coma, indicating liver. And liver failure accompanied by vomiting and diarrhea people associate it more with kidney disease the entire blood passes. Fargo, ND 58103 in treating liver disease and preventing serious signs develop high liver copper by! Condition and lead to a variety of infectious diseases: because the entire volume! Easy to miss normal: Borst / EyeEm hepatic encephalopathy is another common sequelae liver... Is chronic, end-stage liver failure, it is especially susceptible to a sudden and severe in.

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